Gleason Score / ISUP Grade Group
Grades prostate cancer aggressiveness to guide treatment decisions and prognosis
- Highest activation tier
- Mandatory
- How it is scored
- Scored in code; a stated value is compared only from the structured summary or a supplied value
- Scoring type
- classification
- Care settings
- Inpatient, Outpatient
When it activates
Scribeable activates a calculator from the encounter. The Gleason Score / ISUP Grade Group can activate when the transcript or pasted chart context documents any of these:
- Prostate cancer grading
- Prostate biopsy interpretation
- Prostate cancer treatment planning
A coded diagnosis can also activate it. ICD-10 prefixes carried by the registry: C61.
Inputs the note needs
2 inputs. Each is resolved from the transcript, the pasted chart context and charted labs; an input marked "asks you" is requested as a clarification when it is undocumented.
| Input | Type | Unit / options | Guidance |
|---|---|---|---|
| Gleason sum score (6-10)optional | exam | ||
| ISUP Grade Group (1-5)optional | exam |
Scoring
GG1=Gleason ≤6 (3+3), GG2=7 (3+4), GG3=7 (4+3), GG4=8, GG5=9-10.
Interpretation
GG1 (Gleason 6): Very low risk — active surveillance. GG2 (3+4=7): Low-intermediate risk. GG3 (4+3=7): Intermediate risk — treatment generally recommended. GG4 (Gleason 8): High risk — definitive treatment. GG5 (Gleason 9-10): Very high risk — multimodal therapy.
Evidence
Sources carried in Scribeable's citation registry for this calculator; guideline version: Epstein 2016.
- Epstein JI et al. The 2014 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic CarcinomaEpstein et al. (Gleason/ISUP) 2016 · 2016 · ISUP · Consensus · link last verified 2026-03-28
How Scribeable handles it in the note
When an encounter activates the Gleason Score / ISUP Grade Group at the mandatory tier, Scribeable resolves its inputs from the transcript, the pasted chart context and any charted labs, and asks you for a missing input you can supply before the note is finalised. Bedside-exam and separately ordered study values are not requested one input at a time; a calculator that carries a combined clarification question may still put that single question to you.
The score is computed in code from the resolved inputs, not recalled by the language model. A stated Gleason Score / ISUP Grade Group value is compared against the computed one when the draft's structured summary carries it; a disagreement found there is flagged to the second drafting pass, which is instructed to correct the score and its interpretation, unless Scribeable has supplied the computed value to that pass, in which case the value the draft writes is checked against the supplied one and a detected difference is shown beside the note for you to adjudicate rather than silently rewritten.
Classified as a staging or classification system: activated strictly, because a wrong stage on the wrong patient is a documentation hazard.
See it activate on your own encounter
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