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Home/Clinical calculators/SLEDAI-2K (Systemic Lupus Erythematosus Disease Activity Index)

Clinical calculator · Rheumatology

SLEDAI-2K (Systemic Lupus Erythematosus Disease Activity Index)

Quantifies lupus disease activity to guide immunosuppressive therapy adjustments

Highest activation tier
Mandatory
How it is scored
Scored in code; a detected disagreeing draft value is flagged for correction
Scoring type
questionnaire
Care settings
Inpatient, Outpatient

When it activates

Scribeable activates a calculator from the encounter. The SLEDAI-2K (Systemic Lupus Erythematosus Disease Activity Index) can activate when the transcript or pasted chart context documents any of these:

  • SLE disease activity assessment
  • Lupus flare evaluation
  • Immunosuppressive therapy adjustment

A coded diagnosis can also activate it. ICD-10 prefixes carried by the registry: M32.

  • SLE M32.0

Note-type scope: it activates on notes whose subject resolves to rheumatology. A note that resolves to another subject does not carry it even when the clinician's specialty matches; a note with no resolvable subject (a generic consultation) falls back to the specialty match.

Inputs the note needs

1 input. Each is resolved from the transcript, the pasted chart context and charted labs; an input marked "asks you" is requested as a clarification when it is undocumented.

InputTypeUnit / optionsGuidance
SLEDAI-2K total score (0-105)exam

Reference for licensed clinicians. Where the registry text carries dose thresholds or conversion factors, they are as published in the cited sources. This page is not a prescribing tool and not individualised medical advice; verify against a current drug reference and the current guideline before acting. Medical disclaimer.

Scoring

24 weighted items across 9 organ systems. Total 0-105.

Interpretation

0: Inactive. 1-5: Mild activity. 6-10: Moderate activity. 11-19: High activity. ≥20: Very high activity — aggressive immunosuppression needed.

Evidence

Sources carried in Scribeable's citation registry for this calculator; guideline version: Gladman 2002.

  • Bombardier C et al. Derivation of the SLEDAI — a disease activity index for lupus patients (SLEDAI-2K)Bombardier et al. (SLEDAI) 2002 · 2002 · Level I · link last verified 2026-03-28

How Scribeable handles it in the note

When an encounter activates the SLEDAI-2K (Systemic Lupus Erythematosus Disease Activity Index) at the mandatory tier, Scribeable resolves its inputs from the transcript, the pasted chart context and any charted labs, and asks you for a missing input you can supply before the note is finalised. Bedside-exam and separately ordered study values are not requested one input at a time; a calculator that carries a combined clarification question may still put that single question to you.

The score is computed in code from the resolved inputs, not recalled by the language model. If the draft states a SLEDAI-2K (Systemic Lupus Erythematosus Disease Activity Index) value that disagrees with the computed one, the disagreement is flagged to the second drafting pass, which is instructed to correct the score and its interpretation before you see the note.

Classified as a risk score: activated strictly, by a documented trigger, never by a permissive reading of the encounter.

Related calculators

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  • Medsger Severity Score (Systemic Sclerosis)Grades organ involvement severity in systemic sclerosis for prognosis and treatment
  • Beighton Hypermobility ScoreScreens for generalized joint hypermobility to support diagnosis of hypermobility spectrum disorders and Ehlers-Danlos syndrome

Can activate in: Rheumatology.

Scored in code

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