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R65.20R65.21A41.01A41.02+9 more

Sepsis

Life-threatening organ dysfunction caused by a dysregulated host response to infection.

Fever or hypothermiaTachycardiaTachypneaAltered mental statusHypotension

Key Documentation Elements

  • •Sepsis criteria met (SIRS, qSOFA, SOFA score)
  • •Suspected or confirmed infection source
  • •Blood culture timing and results
  • •Antibiotic selection, timing, and de-escalation
  • •Organ dysfunction markers (lactate, creatinine, bilirubin)

Documentation Challenges

  • •Documenting sepsis criteria (qSOFA, SOFA) and onset time
  • •Capturing source of infection and organism identification
  • •Recording SEP-1 bundle compliance elements and timing
  • •Tracking organ dysfunction and severity progression

Billing Considerations

  • •Severe sepsis (R65.20) vs septic shock (R65.21) distinction
  • •Underlying organism coding (A41.x) required with R65.2x
  • •Critical care time documentation for billing

Frequently Asked Questions

What ICD-10 codes are used for sepsis?

Severe sepsis uses R65.20, septic shock uses R65.21, and underlying organism codes (A41.x) are required as additional codes. For example, MRSA sepsis uses A41.02 with R65.20. Scribeable captures organism and severity for dual coding.

How does Scribeable help with sepsis documentation?

Scribeable captures sepsis criteria, bundle element timing, organ dysfunction markers, antibiotic decisions, and culture results from your encounter, ensuring SEP-1 compliance documentation and accurate severity coding.

Automate Sepsis Documentation

Scribeable captures all required elements for Sepsis from your patient conversation. AI-assisted ICD-10 coding and HCC capture.

ICD-10 Codes

R65.20R65.21A41.01A41.02A41.1A41.2A41.50A41.51A41.52A41.53A41.59A41.89A41.9

Related Specialties

critical careemergency medicinehospitalistinfectious disease

Related Conditions

Hep C

Viral infection of the liver caused by the hepatitis C virus, often progressing to chronic disease.

B18.2B17.10

HIV

Retroviral infection affecting the immune system, managed with antiretroviral therapy.

B20Z21

C. diff

Toxin-mediated colitis caused by Clostridioides difficile, typically following antibiotic exposure.

A04.71A04.72

Cellulitis

Acute bacterial infection of the skin and subcutaneous tissues causing spreading erythema and inflammation.

L03.011L03.012

Calculators this diagnosis can activate

Registry entries whose ICD-10 trigger prefixes match Sepsis's codes. Each page lists the inputs the note needs, the scoring criteria and the cited sources.

  • Mean Arterial Pressure (MAP)Calculates mean arterial pressure to assess end-organ perfusion adequacy
  • qSOFA ScoreIdentifies non-ICU patients with infection at high mortality risk
  • SIRS Criteria (Systemic Inflammatory Response Syndrome)Identifies systemic inflammatory response to guide early sepsis recognition and management
  • SOFA ScorePredicts ICU mortality based on organ dysfunction
Browse the full registry

Sepsis Documentation Guide

Life-threatening organ dysfunction caused by a dysregulated host response to infection.

ICD-10 Codes: R65.20, R65.21, A41.01, A41.02, A41.1, A41.2, A41.50, A41.51, A41.52, A41.53, A41.59, A41.89, A41.9

Common Symptoms

  • Fever or hypothermia
  • Tachycardia
  • Tachypnea
  • Altered mental status
  • Hypotension

Key Documentation Elements

  • Sepsis criteria met (SIRS, qSOFA, SOFA score)
  • Suspected or confirmed infection source
  • Blood culture timing and results
  • Antibiotic selection, timing, and de-escalation
  • Organ dysfunction markers (lactate, creatinine, bilirubin)

Documentation Challenges

  • Documenting sepsis criteria (qSOFA, SOFA) and onset time
  • Capturing source of infection and organism identification
  • Recording SEP-1 bundle compliance elements and timing
  • Tracking organ dysfunction and severity progression

Billing Considerations

  • Severe sepsis (R65.20) vs septic shock (R65.21) distinction
  • Underlying organism coding (A41.x) required with R65.2x
  • Critical care time documentation for billing

Frequently Asked Questions

What ICD-10 codes are used for sepsis?

Severe sepsis uses R65.20, septic shock uses R65.21, and underlying organism codes (A41.x) are required as additional codes. For example, MRSA sepsis uses A41.02 with R65.20. Scribeable captures organism and severity for dual coding.

How does Scribeable help with sepsis documentation?

Scribeable captures sepsis criteria, bundle element timing, organ dysfunction markers, antibiotic decisions, and culture results from your encounter, ensuring SEP-1 compliance documentation and accurate severity coding.

Related Conditions

  • Hep C
  • HIV
  • C. diff
  • Cellulitis

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